![]() In developing the LEAP approach, including LEAP-FI, the Taskforce has built on and integrated existing, high-quality nature-related frameworks, tools, data sources and other guidance developed by a range of other organisations that are aligned with the TNFD’s principles and approach. LEAP and LEAP-FI aim to meet the needs of five types of financial institutions as both users and beneficiaries of the approach: However, for the financial services sector as providers of financial capital, different entry points into the LEAP approach and a greater or lesser emphasis on different components of LEAP may be appropriate. The TNFD believes that all aspects of the TNFD LEAP approach should be incorporated by all types of organisations into any robust nature-related risk and opportunity assessment process. Complex financial products such as derivatives are not included within the scope of the LEAP approach. debt and equity investing, trading and insuring). This LEAP-FI focuses on the assessment of nature-related risks and opportunities in relation to financed activities (e.g. With these complexities and nuances in mind, the TNFD has developed an extended LEAP approach for financial institutions (LEAP-FI). In such cases, the LEAP approach can be used as a checklist to ensure existing internal processes adequately address nature-related risks and opportunities. The TNFD also recognises that some organisations may already have an equivalent process built into their enterprise risk management framework. Financial institutions, in particular, have different decision making and information requirements to corporates and there is significant difference among financial institutions. The TNFD recognises that a general approach is difficult to develop, given variations in business models, sector-based market dynamics and the information needs of users. This prototype of LEAP has been designed as a general approach for use by a wide range of corporates and financial institutions. ![]() Not everything that is identified, assessed and evaluated using the LEAP approach needs to be disclosed. As such, not everything that is identified, assessed and evaluated using the LEAP approach needs to be disclosed. LEAP is not, in itself, a recommended disclosure or a mandated process to adhere to the disclosure recommendations put forward by the TNFD.
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![]() You can also get the current source directly from the git Async reader fixes in GStreamer support.īinary packages for various distributions will be available from: Character tables updated to Unicode 15.0.0. Vive seems to work right out of the box and they clearly seen the issues with usb so they avoided it for power supply.Wine Announcement The Wine development release 7.18 is now available. I am not sure the rift is the right choice anymore. Really disappointed that something like this would be allowed to be shipped out this unpolished. I’ve done everything I possibly could before I made this post. I am not a person to complain, but this whole situation really has me upset. Why do this? USB should be strictly for sensor data, not power when it comes to something like this. The limits are being pushed on a usb 3.0 standard that is already unstable because of manufacturing practices. Next why on earth was it ever thought to be a good idea to power 2 screens, the oculus system board, 5 sensors / cams with a single usb 3.0 port. a standard window with a proper frame on it would have done just fine. Again why make things complicated when it could have been made so much simpler? I know it can’t be aesthetics because there is nothing pretty about that installation window. Try to drag the window up and it just snaps back down behind the task bar. It falls behind the windows taskbar at the bottom of the screen and there is no way of recovering that. If you even drag the window what so ever the button to advance to the next step will be totally unclickable. At least show some reasonable error messages so I can figure out what the issue may be. How does something SOMETIMES install? I’ve never seen that. It baffles me how you guys could even pull something off like that. ![]() What really amazes me here is that if you attempt to install it enough times it will eventually install. Installion fails with no reason why displayed. Okay- i’ve finally made it through the tedious download process. Again was it really that unreasonable to put incremental downloading system in place? My download failed at 5.5gb of 7.18gb- why is it that I have to redownload from the start when 5.5gb of it was already downloaded. Instead of picking up where the download left off once your connection returns you are forced to delete what was already downloaded and start over fresh. If at any point during the download your connection is interrupted the installation will fail, but it doesn’t fail nicely. The download is 7.18GB a number burned into my head at this point. Let’s start with the download once you run the setup. I’ve seen amatuer software more polished than this. I found it hard to believe this software was pushed out by a multi billion dollar company. Why doom your device from the start with something so unreliable? ![]() Was it really that unreasonable to put a simple wall outlet plug on there? Something standard that will work. Usb is the wild west when it comes to quality. I question the reason oculus would decide to power a device over usb 3.0 when everyone knows usb is unreliable at best when it comes to that. Even the first dev kit oculus worked right out of the box for me. This is the rant part- I am honestly pretty dissapointed and defeated right now. Made sure rift doesn’t power off in the usb settings.Īdded a usb 3.0 powered hub thinking that maybe for some reason oculus wasn’t getting enough power.ģ0 to 40 times if you count the failed downloads and installations. Made sure that the usb port doesn’t power off in power management settings. Made sure that my camera privacy setting in windows was set properly. Tried 2 different videos cards that I know work. Here is a list of things I’ve tried to fix my issue:Īdding an expansion usb 3.0 card as I heard many usb 3.0 ports don’t do the job properly. So i just stare into the abyss of eternal loading screen. Those vanish aswell, sometimes they come back. Now all I see is the 3 dot loading bar in the middle of my screen and once in a while I will see 2 white dots in the background that respond to my controllers. I put my headset on, i briefly see an oculus logo then it dissapears. So the main issue with my oculus is the black screen. So my system should run oculus no issues. Everything is green checkmark + except processor which is green checkmark. Lemme start by saying my oculus meet and exceeds all requirements. And if anyone can help me out I would be thankful. This thread may be a bit of a rant, but I think it’s justified. Now i’m on day 5 of trying to get this thing to work. 3 of my buddies got it the same day and I thought I was just going to jump right in and play. First of all I want to say that I was super excited when I got my oculus rift s. They showed that Euphorbia tithymaloides has reproduced and evolved in a ring through Central America and the Caribbean, meeting in the Virgin Islands where they appear to be morphologically and ecologically distinct.Įuphorbia tithymaloides was introduced as a garden plant prior to 1688. In 2012, Cacho and Baum described the first example of a ring species in plants. Subspecies are usually identifiable by their leaves, which come in several types such as laurel-like and variegated and which can be tinged with white or red. The plant generally flowers in mid-spring. The seed pod is about 7.5 mm (0.30 in) long and 9 mm (0.35 in) wide, and ovoid in shape (with truncated ends). The male pedicel is hairy, while the female is glabrous. The floral leaves are bifid (split in two parts) and ovate, while the involucral bracts are bright red, irregularly acuminate in shape (e.g., like a slipper), and about 1.1 to 1.3 mm (0.043 to 0.051 in) in length with a long, thin tube. The plant terminates in a dichotomous cyme, with a peduncle supporting each flower. The leaves are glabrous (smooth) and acuminate in shape, with entire (smooth) edges. Each leaf is sessile (attaching directly to the plant), and about 35 to 75 mm (1.4 to 3 in) in length. The leaf is a simple angiosperm leaf, arranged oppositely on the stem. The shrub can grow to 1.8 to 2.4 metres (6 to 8 ft) in height and generally is about 45 to 60 cm (18 to 24 in) in width. The plant requires a sunny area to grow in. The plant tends to be taller and have more biomass if it is well-watered. It is relatively intolerant of high soil salinity levels, but exhibits saline tolerance if well fertilized. It prefers soil that is sandy, well-drained, and nutrient-rich, particularly with higher concentrations of boron, copper, iron, manganese, molybdenum, and zinc. Distribution and description Įuphorbia tithymaloides is native to tropical and subtropical North America and Central America. In other parts of the world, it is known as gin-ryu (Japan) pokok lipan and penawar lipan (Indonesia) airi, baire, and agia "rang chita" (Bengal),(India) aperejo (Yoruba) sapatinho do diabo (Brazil) ítamo real (Cuba and Puerto Rico) pantoufle (France) and zapatilla del diablo (Mexico). Among them are redbird flower, devil's-backbone, redbird cactus, Jewbush, buck-thorn, cimora misha, Christmas candle, fiddle flower, ipecacuahana, Jacob's ladder, Japanese poinsettia, Jew's slipper, milk-hedge, myrtle-leaved spurge, Padus-leaved clipper plant, red slipper spurge, slipper flower, slipper plant, slipper spurge, timora misha, and zig-zag plant. Names Įuphorbia tithymaloides has a large number of household names used by gardeners and the public. However, the genus Pedilanthus has been submerged into the genus Euphorbia, and is more correctly known by its new name ( Euphorbia tithymaloides). An erect shrub, the plant is also known by the scientific name Pedilanthus tithymaloides. Euphorbia tithymaloides is a perennial succulent spurge. ![]() You should contact customer service department. I have an Android device version 4.0.3 or higher, but I'm still experiencing some technical difficulties with the RealPlayer Android App, what should I do?.You should upgrade your Android device to latest version. I don't have an Android device with version 4.0.3 or higher, what should I do?.Desktop browser with latest available updates.What are the system requirements for get RealPlayer App?.Software has a support team that will answer any questions or concerns that the user has. Application download RealPlayer free has a FAQ section, a help section that can help user with any questions or problems they’re having. There are extensive FAQs that are helpful. SupportĬompany has an email support line, but it is difficult to get through. It can be used to playback capture audio and video, to view and download video, audio files, to stream live multimedia, to record live streams. Software install RealPlayer has a lot of functionality. There are some features that are locked on some devices, but they are unlocked more expensive devices. Product is easy to download and navigate. Interface is very intuitive, user only needs a few minutes to get used to it. It's easy to find a video or audio file and to open it. It is easy to find your favorite TV shows with the tabs provided, but it can be difficult to find your favorite music without scrolling through a long list. Interface at free RealPlayer can be little cramped on phones, but it is straightforward. Software is easy to use, but it can be a little challenging to find certain things. When users click on a specific point in timeline, the audio or video will play from that point onward. One of the best features of application is timeline. It contains a menu bar, a playback progress bar, a timeline, video/audio player. Interface of RealPlayer application is very simple. This sidebar not only gives user access to different categories of videos and audio files, but to videos, radio streaming channels. Interface has a sidebar where users can find different categories and files: Home, Films, TV Shows, TV Channels, Radio, Music, Comedy, Podcasts, Sports, Apps, Live. User can browse and play videos and audio files, folders with one click. ![]() It provides a home screen with list of all videos/audio files and folders. It is easy to navigate and simple to use. Interface of RealPlayer Mac app is very simple. Some of these tabs are locked on some devices, they are unlocked on more expensive devices. Interface is very straightforward, with tabs for movies, TV, music, recorded TV, photos, and customizable shortcuts. Interface is easy to use, it can be a little cramped on phones. Goal of program is to make it easy for people to listen to and watch their media files. It is an application that is free to download and use, but does have a paid version. This application is a cross-platform software that can be used on computers running Windows, Mac OS, Linux. One of the most popular programs for playing media files is RealPlayer free download. It is available on Android, iOS, Windows, Mac, on web. ![]() It is made by RealNetworks, a company that has been around since 1994, is now on its third generation of apps. Easily downloaded for free on many different devices, RealPlayer download is one of the most popular media players around. While Home is where you’ll increasingly find community through your passions and interests, you can continue to stay up-to-date on the people and communities you care about most in Feeds. We’re investing in AI to best serve recommended content in this ranked experience. This system takes into account thousands of signals to help cut through the clutter and rank content in the order we think you will find most valuable. Color coding your conversation can make it easier to identify contacts and give each chat a personal touch. ( KCTV /Gray News) - A shooting at a nightclub in Kansas City, Missouri, left three people dead and two more injured early Sunday morning, KCTV reports. Your Home tab is uniquely personalized to you through our machine learning ranking system. Tap the dropdown menu next to the shortcut, then select Pin, Auto or Hide. We all know someone who posts all the time on Facebook: An uncle shares too many political rants. If you still have problems, refer to sections 10 and 11 below for tips on troubleshooting deeper Facebook errors. Tap on your shortcut bar and select Settings & privacy. Try tagging someone else and see if that works. From Home, you can also create a Reel, see what your connections are sharing on Feed and in Stories, and build community over new and shared interests. Open the Facebook app for iPhone, iPad or Android. This is where you will discover new content through recommendations in addition to connecting with your friends and family. OUTDATED FUNCTION AND NO LONGER RELEVANTAre annoyed by the new sidebar or 'ticker' on Facebook Then here is a quick 'how to video' to turn it off http://w. Find all usage guide, troubleshooting tips and resources for your HUAWEI. We’re introducing the name Home for the tab you see when you first open the Facebook app. Learn about Some app icons are missing from my HUAWEI phone/tablets home screen. You can also personalize and pin a tab in your shortcut bar, making its placement permanent. If someones name has disappeared from the facebook sidebar that has always been on it, what happened The name has been on my list since we became facebook friends about 1 1/2 years ago and now there name no longer shows on the side bar. The tabs in the shortcut bar change based on the parts of the app you’re using the most. We expect these updates to be rolled out globally over the next week. Starting today, some people will see Feeds as a tab in their shortcut bar on iOS, this bar is found at the bottom of the app, and on Android, it’s found at the top. ![]() T here are no Suggested For You posts in Feeds and ads are included. As Home becomes more of a discovery engine for you to find and follow new content and creators through recommendations, the Feeds tab provides an easy way to access the content from the people and communities you’re already connected with on Facebook. There are times you might know just what you’re looking for - say, the latest posts from your groups - or you may want to encounter fresh, entertaining content. We understand you may want more options when it comes to sorting and seeing your content. Now all of a sudden it Only shows up in a totally different state and with exact name search. Your account password is maintained by your login provider: either Google, Facebook, Apple, Pokemon Trainer Club, or Niantic Kids. Is there something I could do to send signals to Google to show that I am in Matthews, NC?Ģ months ago my listing quit showing up at all unless you typed exact business name ![]() What could possibly cause my listing or Google to do this? I have been without my listing for a few months now and have NO calls coming in from it. The 23-year-old man was attacked early Sunday behind a bar in Port Charlotte, Florida, according to the Florida Fish and Wildlife Conservation Commission. If you search Locksmith Independence, KS it shows up on the maps. If you search Locksmith Matthews, NC my listing does not show up at all. Keep in mind the GMB is in Matthews, NC All my service areas and the actual map show the correct areas. Facebook uses the shortcut bar at the bottom of the app as a way for you to quickly and easily navigate to different sections of Facebook. Once you’re here, click on privacy and settings. To get back the Events shortcut, you will have to go on Facebook and navigate over to the settings. You will just have to go into your settings and manually add the events shortcut. Now if I search my business name under the auto populate I see it with Independence, KS on the listing. Do not worry if the events tab has gone missing, as it is quite an easy fix. Website design, Social Media marketing and Email marketing provided by SpotHopper. I pretty much do not have any traffic, views or calls now. The Bar will be open regular hours Monday-Thursday 9:00am-2:30am. Posted about my SAB listing a few weeks ago about not showing up in search only when you entered the exact name. *By purchasing F1 2013: COMPLETE EDITION you will own all available game content for the game. The game features all eleven teams and twenty-two drivers competing in the 2013 season, as well as the nineteen circuits and Grands Prix. GLORIOUS FORMULA ONE - F1 2013 will immerse you in the world's most visually striking sport with new graphical improvements and more realistic AI driver behaviour.MID-SESSION SAVES - New mid-session saves let you complete a long race weekend at your own pace rather than commit to completing the full session in one go.GRAND PRIX MODE RETURNS - Step into the shoes of your favourite driver and compete in a single race or full season in the pursuit of racing glory.RACENET - Track your stats and get new objectives and challenges every week with RaceNet, Codemasters' free online community hub, AND receive the iconic 1976 Ferrari 312 T2 as driven by Niki Lauda, which featured in the motion picture Rush, when you sign up!.MULTIPLAYER - Prove yourself in split-screen or online in co-op championships and against 16 players plus 6 AI to simulate full 22 car grids.NEW F1 CLASSICS MODE - Race on grids featuring cars from different years in single-player, split-screen and online multiplayer.CLASSIC CONTENT - Features classic content with cars, drivers and circuits from the 1980s and 1990s.ALL THE CARS, ALL THE STARS - Features all the cars, stars and circuits from the 2013 FIA FORMULA ONE WORLD CHAMPIONSHIP.Choose between official stores and keyshops. For example, if you want to get F1 2013 Classic Edition Steam key and activate it on Steam, pick the shop that has a Steam icon. F1 2013: COMPLETE EDITION - F1 2013 expanded with all available additional classic content for F1 2013 for the definitive FORMULA ONE videogame experience F1 2013 Classic Edition sale & discount - all in one place. If you’re invoicing more than once or twice a month it makes a lot of sense to switch to an invoicing software.
Long Beach began recycling last December to comply with state law. Cities must reduce their trash flow 25% by 1995, and 50% by 2000, to conserve scarce landfill space. “If people don’t participate because of scavengers, then it’s a problem for us,” said James R.Ĭities that don’t meet those goals could face fines of up to $10,000 per day. Technically, it has long been illegal to pick through trash in Long Beach. The maximum punishment is a $500 fine and six months in jail. But the law was rarely enforced before the new recycling program.Ĭity officials say they do not usually cite scavengers who take cans and other recyclables from trash cans, but those who pilfer recycling bins do so at their own risk, said recycling spokeswoman Rita Hooker. Police recently began writing $135 citations, although no one has kept track of how many. So far, no one has been arrested and jailed, officials said. Some of the scavengers begin as early as 3 a.m., but most start around sunrise. Guadalupe Estrada, 68, moved down the street on a recent morning seeking his livelihood in the trash cans and recycling bins of a central Long Beach neighborhood.Įstrada, wearing a straw hat and hauling a bag of cans, bypassed the bin in front of Betty Marshall’s home. She was out watering her lawn at about 7:30 a.m. Some people yell at him as if he were a common thief. “I am a very humble man,” said Estrada, who lives alone and buys food and other necessities with the money he earns scavenging, about $5 a day. ![]() Juan Medina headed out at 5:30 on another morning in search of recyclables with his daughter and 13-year-old grandson. The three hurried through the alleys behind the homes surrounding Junipero Avenue. Medina and his daughter used tools made from broom handles to fish bottles and cans out of the trash. The boy, out of school for summer break, pulled a homemade plywood wagon. They stopped to search a large trash bin while a transient covered with flies slept a few feet away. A trio of kittens nipped at scraps and darted in and out of drain pipes. Medina said he was unemployed, and the $5 to $10 a day they received for their efforts helped keep a roof over the family’s head and food on the table. Right now, there’s no other way to get food.” “We’re not working right now,” said the daughter, who declined to give her name or details about how they make ends meet. On another morning, in another alley a few miles away, Fleming Robinson scavenged to supplement his $315 monthly welfare check. Robinson, 57 and unemployed, said he has worked the streets of Long Beach seven years, taking in about $100 a week. Trash bins are usually full of bottles and cans after Friday, which is payday for many people. The first to the 10th of the month also is prime time-just after welfare and Social Security checks arrive. ![]() ![]() Robinson drives to neighborhoods throughout Long Beach and then sets out on foot. He usually avoids affluent areas like Belmont Shore. “I go there once in a while,” said Robinson, who lives in an apartment on Martin Luther King Jr. “But you have to watch where you park, and people think you’re doing something wrong. The scavengers interviewed by The Times said they resist taking cans and bottles from recycling bins. It just takes too many cans to cover a $135 citation-about 3,900 at current recycling rates. ![]() He treats me like a queen just like you, just like you do “Cause daddy he loves me just like you do “Daddy” is a real tear-jerker that talks about a woman getting proposed to and running to her dad to show him the engagement ring. She should know she’s royalty.” “Daddy,” – Abby AndersonĬountry singer Abby Anderson wanted to write a song that details her everlasting love for her father. “I need a man who loves me like my father loves my mom A truly heartwarming tribute to what a woman should look for in a partner a man who loves her as much as her dad loves her mum. Jax said she gifted this song to her father on Father’s Day. “Like My Father” is a sentimental song that talks about the perfect example of a loving dad. Love his daughter more than I love you.” “Like My Father,” – Jax It’s a beautiful tune that details just how much a father loves his daughter. This heartfelt track was nominated for an Academy Award and was featured in The Wild Thornberrys Movie. Paul Simon describes this song as “an ode to my lovely daughter.” Lyrics You’ll Loveīut isn’t she lovely, made from love?” “Father and Daughter,” – Paul Simon Stevie was able to transfer so many emotions by not just singing the song, but by also playing all the instruments himself (including some beautiful improvised harmonica). Stevie Wonder’s iconic hit, “Isn’t She Lovely,” is dedicated to his daughter Aisha. ![]() Roles of Gut Microbiome in Systemic Homeostasis of Adaptive Immune Repertoire Gastrointestinal Tract as a Key Site for Systemic Immune Modulation ![]() ![]() In this article, we highlight the recent advancement in high-throughput immune repertoire analysis by next-generation sequencing (NGS) and its possible application in future studies to elucidate previously unrecognized mechanisms of immune modulation by gut microbiota and oral nutrition. For instance, several groups have reported pivotal observations that alloimmune-mediated graft-versus-host reactions in the setting of hematopoietic cell transplantation and immune responses against malignant neoplasms triggered by immune checkpoint inhibition are associated with the abundance of distinct members of intestinal commensal flora ( 4– 8). Furthermore, until recently, there had been no available technologies that comprehensively identify each of TCR and BCR/Ig clonotypes constituting the whole adaptive immune cell repertoire.ĭuring the past few decades, accumulative lines of evidence have indicated that the host microbiome and nutrients not only play key roles for balancing the host immunity in health and disease but have a tremendous influence on the generation and shaping of immune cell repertoire ( 2, 3). However, the underlying mechanism by which these repertoires are ontogenetically developed and shaped is largely unknown. It is well-characterized that such huge diversity of antigen-specific receptors is created through somatic rearrangement of variable (V), diversity (D), and joining (J) (or V and J) gene segments located in TCR- or BCR/Ig-encoding loci and the concomitant incorporation of random nucleotide insertions and deletions. At the individual level, the estimated number of TCR and BCR/Ig clonotypes is from a few thousands to more than billions depending on the species of animal, which is believed to form the basis of the host ability to cope with innumerable immunologic threats. At the single-cell level, these cells express a single type of unique antigen-specific receptors: T-cell receptor (TCR) for T cells and B-cell receptor/immunoglobulin (BCR/Ig) for B cells that define a phenotypic clone or a clonotype of these immune cells. In this paradigm of the “adaptive” immune system, it is firmly believed that pre-existing repertoire of two types of lymphohematopoietic cells, classic T cells and B cells, predominantly determine the mode and pattern of immune responses in a given individual. The jawed vertebrates have evolutionally acquired a unique immune system consisted of effector and regulator cells that can effectively respond or establish tolerance to millions of endoneous and environmental antigens in an epitope-specific manner ( 1). Accumulation of such knowledge will lead to the development of effective ways for personalized immune modulation through deeper understanding of the mechanisms by which the intestinal environment affects our immune ecosystem. Although there are still unsolved caveats, this emerging technology combined with single-cell transcriptomics/proteomics provides a critical tool to unveil the previously unrecognized principle of host–microbiome immune homeostasis. In this article, we aim to discuss the possible application of high-throughput immune receptor sequencing in the field of nutritional and intestinal immunology. Sophisticated immuno-bioinformatic analyses by use of this innovative methodology have been already implemented in clinical development of antibody engineering, vaccine design, and cellular immunotherapy. Over the past several years, high-throughput next-generation sequencing has been developed as a powerful tool to profile T- and B-cell receptor repertoires in a given individual at the single-cell level. Acquired immunity against various microorganisms including host microbiome is principally founded on T cell and B cell populations, each of which expresses antigen-specific receptors that define a unique clonotype. Although advances in modern immunology have revealed a role of many unique immune cell subsets, technologies that enable us to capture the whole landscape of immune responses against specific antigens have been not available to date. The human immune system is a fine network consisted of the innumerable numbers of functional cells that balance the immunity and tolerance against various endogenous and environmental challenges. 4Department of Rheumatology and Clinical Immunology, Clinical Research Center for Rheumatology and Allergy, National Hospital Organization Sagamihara Hospital, Sagamihara, Japan.2Repertoire Genesis Incorporation, Ibaraki, Japan.1Department of Hematology and Oncology, Research Institute for Radiation Biology and Medicine (RIRBM), Hiroshima University, Hiroshima, Japan. |
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